Chili Relleno Casserole

Follow this easy recipe for Chili Relleno Casserole made with Bisquick, green chilies, and two kinds of cheese. It’s creamy, cheesy, and great for a meatless meal.

a slice of chili relleno casserole and a fork on a plate

What Is Chili Relleno?

An authentic Chili Relleno is a chili pepper stuffed with cheese and sometimes with meat. It’s usually fried or grilled. I really love Chili Relleno, but it’s time-consuming. That’s why I really enjoy this casserole. It might take 50 minutes to bake, but the prep is really simple.

chili relleno casserole in a glass baking dish

How to make Chili Relleno Casserole

This is such an easy recipe to make. The prep work is a breeze. You just mix up the ingredients and then layer them in the casserole dish.

It will take about 45-50 minutes to bake in the oven.


Here’s what I put in my casserole:

  • Shredded Cheese – I used sharp cheddar because it has the best flavor. You can use any combination of cheeses for it. I also use Monterey Jack to make it nice and cheesy.
  • Butter to help keep the casserole from sticking to the baking dish.
  • Eggs – The egg-size doesn’t matter. You just need 3 eggs of any size.
  • Milk – If you can’t have cow’s milk, you can use almond milk instead.
  • Bisquick – If you are on a gluten-free diet you can use a gluten-free substitute
  • Chilies – I used Ortega whole and diced green chilies. The canned ones have a better texture and last longer on the shelf.

chili relleno casserole ingredients

Does Relleno have meat?

The main stuffing for the chili pepper is cheese. It is optional to add meat such as ground beef, pork, or chicken.

Can you freeze Chili Relleno Casserole?

Yes, this makes an excellent freezer meal. Before you bake it, seal it and put it in the freezer. Label it with the date. It will last about 3 months in the freezer.

When you are ready to bake it, take it out of the freezer the night before and let it thaw in the refrigerator. Then, bake it like normal.

slice of chili relleno casserole on a plate

What do you serve with Chili Relleno Casserole?

This could be a meal all on its own. But if you want some side-dish ideas, try one of these.

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a slice of chili relleno casserole and a fork on a plate
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Chili Relleno Casserole II

Chili Relleno casserole is your favorite flavors without all of the work and oil of frying Chili Rellenos. 
Course Main Course
Cuisine Mexican
Keyword Chili Relleno Casserole
Prep Time 10 minutes
Cook Time 45 minutes
Total Time 55 minutes
Servings 10
Calories 296kcal


  • 1 7 ounce whole chilies
  • 1 4 ounce can diced chilies
  • 2 tablespoons butter
  • 3 eggs
  • 8 ounces shredded Cheddar cheese
  • 8 ounces Shredded Monterey Jack Cheese
  • 2 cups milk
  • 1 cup Bisquick baking Mix


  • Preheat oven to 325.
  • Combine Cheeses in a bowl.
  • Melt butter in 13" x 9" casserole dish. You can do this by placing the butter into the baking dish while the oven is preheating.
  • Lay whole chilies on melted butter, covering bottom of dish. Sprinkle 2/3 of the cheese on chilies.
  • Mix the milk, eggs, Bisquick until smooth, add diced chilies and pour over cheese. Top with remainder of cheese. Bake for 45 minutes.


Calories: 296kcal | Carbohydrates: 10g | Protein: 15g | Fat: 21g | Saturated Fat: 12g | Cholesterol: 104mg | Sodium: 475mg | Potassium: 142mg | Fiber: 0g | Sugar: 4g | Vitamin A: 620IU | Calcium: 417mg | Iron: 0.9mg

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